Throughout his formative years in St. Mel Catholic Parish Grammar School, Thomas Murphy was continually exposed to idea of considering a vocation to the priesthood. As his grammar school studies concluded, he, at the age of 14, decided to give the idea of hearing a call to vocation serious consideration.
At the time, the Archdiocese of Chicago operated a dedicated high school for boys who were seriously considering a vocation to the priesthood. The future archbishop enrolled as a freshman at Archbishop Quigley Preparatory Seminary School in the Fall of 1946.
Archbishop Quigley Preparatory Seminary School closed its doors in 2007. The Archdiocese of Chicago converted the beautiful and historic campus into its headquarters. A portion of the campus is also dedicated to use as a pastoral center.